Mark Santos, PhD

Assistant Professor of Microbiology & Immunology
Mark Santos
Basic Sciences
Staff
Fax
(702) 777-1799

Start Biography

Corbeil D, Santos MF, Karbanová J, Kurth T, Rappa G, Lorico A. Uptake and Fate of Extracellular Membrane Vesicles: Nucleoplasmic Reticulum-Associated Late Endosomes as a New Gate to Intercellular Communication. Cells. 2020;9(9):E1931. Published 2020 Aug 21. 

Osti, D., Bene, M. D., Rappa, G., Santos, M., Matafora, V., Richichi, C., Faletti, S., Beznoussenko, G. V., Mironov, A., Bachi, A., Fornasari, L., Bongetta,D., Gaetani, P., DiMeco, F., Lorico, A., & Pelicci, G. (2019). Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients. Clinical Cancer Research, 25 (1), 266–276. https://doi.org/10.1158/1078-0432.CCR-18-1941

Rappa, G., Puglisi, C., Santos, M. F., Forte, S., Memeo, L., & Lorico, A. (2019). Extracellular Vesicles from Thyroid Carcinoma: The New Frontier of Liquid Biopsy. International Journal of Molecular Sciences, 20 (5), 1114. https://doi.org/10.3390/ijms20051114

Santos, M. F., Rappa, G., Karbanova, J., Vanier, C., Morimoto, C., Corbeil, D., & Lorico, A. (2019). Anti-human CD9 antibody Fab fragment impairs the internalization of extracellular vesicles and the nuclear transfer of their cargo proteins. Journal of Cellular and Molecular Medicine, 23 (6), 4408–4421.  https://doi.org/10.1111/jcmm.14334

Santos, M.F., Rappa, G., Karbanová, J., Kurth, T., Corbeil, D., and Lorico, A. (2018). VAMP-associated protein-A and oxysterol-binding protein-related protein 3 regulate the entry of late endosomes in the nucleoplasmic reticulum. Journal of Biological Chemistry, 293, 13834–13848.

Rappa, G., Conigliaro, A., Santos, M.F., Alessandro, R., and Lorico, A. (2017). Cancer relevance of signal recognition particle RNA and other non-coding RNAs in extracellular vesicles. Translational Cancer Research, 6, S1257–S1260.

Rappa, G.1, Santos, M.F.1, Green, T.M., Karbanová, J., Hassler, J., Bai, Y., Barsky, S.H., Corbeil, D., and Lorico, A. (2017). Nuclear transport of cancer extracellular vesicle-derived biomaterials through nuclear envelope invagination-associated late endosomes. Oncotarget, 8, 14443–14461

Green, T.M., Santos, M.F., Barsky, S.H., Rappa, G., and Lorico, A. (2016). Analogies between cancer-derived extracellular vesicles and enveloped viruses with an emphasis on human breast cancer. Current Pathobiology Reports, 4, 169–179.

Green, T.L.1, Santos, M.F.1, Ejaeidi, A.A., Craft, B.S., Lewis, R.E., and Cruse, J.M. (2014). Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells. Experimental and Molecular Pathology, 97, 44–48.

Santos, M.F., Mannam, V.K.R., Craft, B.S., Puneky, L.V., Sheehan, N.T., Lewis, R.E., and Cruse, J.M. (2014). Comparative analysis of innate immune system function in metastatic breast, colorectal, and prostate cancer patients with circulating tumor cells. Experimental and Molecular Pathology, 96, 367–374.