Rakesh Singh, BPharm., Ph.D.
Dr. Singh is an Assistant Professor of Pharmacology. He received his Bachelor’s degree in Pharmaceutical Sciences from the Birla Institute of Technology in Ranchi, India and PhD in Pharmacology from the University of Kansas.
Before joining Touro, Dr. Singh has taught medical pharmacology in both PA programs and medical schools. He has also taught various topics in pharmacology and physiology in his previous positions at the University of Illinois at Chicago and the University of Kansas.
Dr. Singh’s research has been extensively focused on understanding the underlying cellular and biochemical mechanisms responsible for the pharmacological activity of drugs. His graduate work was centered on atypical antipsychotics.
Ph.D. in Pharmacology - University of Kansas
B.S. in Pharmaceutical Sciences - Birla Institute of Technology
DO & PA: Pharmacology
Funk RS, Singh RK, Becker ML: Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro. Clinical and Translational Science; 25 October 2019.
Singh RK, van Haandel L, Kiptoo P, Becker ML, Siahaan TJ, Funk RS: Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model. Eur J Pharmacol. 2019 Apr 2;853:264-274.
Singh RK, van Haandel L, Heruth DP, Ye SQ, Leeder JS, Becker ML, Funk RS: Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Anti-proliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP. J Pharmacol Exp Ther Feb 2, 2018.
Funk RS, Singh RK, Winefield RD, Kandel SE, Ruisinger JF, Moriarty PM, Backes JM.: Variability in Potency Among Commercial Preparations of Berberine. J Diet Suppl. 2018 May 4;15(3):343-351.
Funk RS, Singh R, Pramann L, Gigliotti N, Islam S, Heruth DP, Ye SQ, Chan MA, Leeder JS, Becker ML: Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro. Clinical and Translational Science; 11 MAY 2016.
Rakesh K. Singh, Jeff L. Staudinger, and Nancy A. Muma. (2008) Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor signaling by atypical antipsychotic drugs. The International Journal of Neuropsychopharmacology Cambridge University Press; 2008 Oct 31:1-15.
Rakesh K. Singh, Jia C, Garcia F, Carrasco GA, Battaglia G, Nancy A. Muma. (2009) Activation of the JAK-STAT pathway by olanzapine is necessary for desensitization of serotonin2A receptor-stimulated phospholipase C signaling in rat frontal cortex but not serotonin2A receptor-stimulated hormone release. J of Psychopharmacology March; 2009.
Shi J, Damjanoska KJ, Singh RK, Carrasco GA, Garcia F, Grippo AJ, Landry M, Sullivan NR, Battaglia G, Muma NA. (2007) Agonist induced-phosphorylation of Galpha11 protein reduces coupling to 5HT2A receptors. J Pharmacol Exp Ther Oct; 323(1):248-56.
Muma NA, Singh RK, Vercillo MS, D'Souza DN, Zemaitaitis B, Garcia F, Damjanoska KJ, Zhang Y, Battaglia G, Van de Kar LD. Chronic olanzapine activates the Stat3 signal transduction pathway and alters expression of components of the 5-HT2A receptor signaling system in rat frontal cortex. (2007) Neuropharmacology. Sep; 53(4):552-62.
Singh RK, Shi J, Zemaitaitis BW, Muma NA. (2007) Olanzapine Increases RGS7 Protein Expression via Stimulation of the JAK-STAT Signaling Cascade. J Pharmacol Exp Ther Jul; 322(1):133-40.
Edwin F, Singh R, Endersby R, Baker SJ, Patel TB. (2006). The tumor suppressor PTEN is necessary for human sprouty 2 mediated inhibition of cell proliferation. J Biol Chem Feb 24; 281(8): 4816-22.
Francis Edwin, Gregory J. Wiepz, Rakesh Singh, Chimera R. Pete, Deepti Chaturvedi, Paul J. Bertics and Tarun B. Patel (2005). A Historical Perspective of EGFR and Related Systems in Epidermal Growth Factor, Methods and Protocols, Methods in Molecular Biology Humana Press, Vol. 327, Page. 224.
American Society for Pharmacology and Experimental Therapeutics
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